Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration
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چکیده
منابع مشابه
Minocycline reduces chronic microglial activation after brain trauma but increases neurodegeneration
Survivors of a traumatic brain injury can deteriorate years later, developing brain atrophy and dementia. Traumatic brain injury triggers chronic microglial activation, but it is unclear whether this is harmful or beneficial. A successful chronic-phase treatment for traumatic brain injury might be to target microglia. In experimental models, the antibiotic minocycline inhibits microglial activa...
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ژورنال
عنوان ژورنال: Brain
سال: 2017
ISSN: 0006-8950,1460-2156
DOI: 10.1093/brain/awx339